A NSF-funded postdoctoral scholar position is immediately available in the laboratory of Dr. Adriana Briscoe at University of California, Irvine. Research in the Briscoe lab is aimed at understanding the molecular basis of color vision evolution in butterflies. The lab has recently developed a new method for expressing invertebrate rhodopsins at levels suitable for functional characterization of rhodopsin absorption spectra (see Frentiu et al. 2015 Molecular Biology and Evolution). The lab is seeking a postdoctoral scholar who will extend this method to develop further insights into the molecular basis of spectral tuning, a form of adaptation to the light environment. To accomplish this, the postdoctoral researcher will use homology modeling, western blot analysis, and functional expression of opsins in HEK293 cells to identify the amino acid residues responsible for the tuning of butterfly rhodopsins across an adaptive radiation.
Successful candidates will collaborate with a dynamic team of behaviorists, electrophysiologists, and evolutionary biologists at UC Irvine and other institutions.
Required qualifications include a Ph.D. in molecular biology, biochemistry, or related fields and demonstrated proficiency with cell culture, western blot analysis, and immunoaffinity purification. Desirable qualifications include expertise in immunohistochemistry, qPCR, and DNA sequence analysis; a strong publication record and excellent writing/communication skills.
Duration of position is dependent upon performance (annual appointments, with potential for renewal), and salary will be on an NIH payscale, commensurate with experience. Applications submitted by February 17, 2017 will be given full consideration, although applications will be reviewed until the position is filled.
Qualified candidates should submit curriculum vitae, a one-page statement of research interests, and names and contact information for three references to the following on-line recruitment URL:
For more information about this position contact Dr. Adriana Briscoe at firstname.lastname@example.org.
Frentiu FD, Yuan F, Savage WK, Bernard GD, Mullen SP, Briscoe AD. 2015. Opsin clines in butterflies suggest novel roles for insect photopigments. Molecular Biology and Evolution, 32:368-79. doi: 10.1093/molbev/msu304
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